Guess I’m back on the topic of Alzheimer’s Disease research again. Jennie Erin Smith’s “Valley of Forgetting: Alzheimer’s Families and the Search for a Cure” is very tightly focused on one particular subset of familial Alzheimer’s being studied in Columbia. This particular form of Alzheimer’s is caused by a mutation in the gene presenilin-1 (PSEN1), E280A. A single amino acid change at position 280 leads to altered protein function. E280A is one of the most common causes of early onset familial Alzheimer’s, and the vast […]
The Faces Behind the Trials
Valley of Forgetting: Alzheimer’s Families and the Search for a Cure by Jennie Erin Smith
